April 27, 2020

NABUMETONE

By Checker Bot

Updated 04-May-2020.

Mondo shtuff from around the internet, all about NABUMETONE!

Compound: NABUMETONE: Molecule Type: Small molecule, Molecular Formula: C15H16O2, Molecular Weight: 228.29, Synonyms: BRL-14777;Nabumetone, Trade Names: Relifex;Relafen;Nabumetone

Nabumetone: MedlinePlus Drug Information: Nabumetone: learn about side effects, dosage, special precautions, and more on MedlinePlus

Nabumetone Monograph for Professionals – Drugs.com: Nabumetone reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).

The use of particle beam mass spectrometry for the measurement of impurities in a nabumetone drug substance, not easily amenable to atmospheric pressure ionisation techniques

Relafen (Nabumetone): Uses, Dosage, Side Effects, Interactions, Warning: Relafen (Nabumetone) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.

My botty best at summarizing from Wikipedia: Nabumetone has been developed by Beecham . it is available under numerous brand names, such as Relafen, Relifex, and Gambaran . nabumetone has little effect on renal prostaglandin secretion . it has less of an association with heart failure than other traditional drugs of the class . as of 2015 the cost for a typical month of medication in the united states is 25 to US$50 . two of them employed HPLC with UV-detection . one HPLC method using direct injection on restricted access biotransformation and disposition studies carried out in humans and minipigs using HPLC with UV, fluorescence and mass spectrometric detection . interactions with gamma-cyclodextrin were also studied by three analytical methods using different techniques along with phosphorescence were also reported . a HPLC method for simultaneous estimation of nabumetone and paracetamol in combined dosage form .