My botty best at summarizing from Wikipedia: Fluocinonide relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort . the usual prescription concentration is 0.05% as a topical cream, ointment, solution fluocinonide ranks as a “high-potency” (second-highest rank) topical corticosteroid . it should not be used if infection is present . fluocinonide is used in veterinary medicine. it is a treatment for allergies in dogs . natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.